The JET tokamak is unique amongst present fusion devices in its capability to operate at high plasma current, providing the closest plasma parameters to ITER. The physics benefits of high current operation have to be balanced against the risks to the integrity of the machine due to high force disruptions. The installation of the ITER-Like Wall (ILW) has added risks due to the thermal characteristics of the metal Plasma Facing Components. This paper describes the operational aspects of the scientific development of high current H-mode plasmas with the ILW, focussing on disruption prediction, avoidance and amelioration. The development yielded baseline H-mode plasmas up to 4MA/3.74T, comparable to the maximum current achieved in JET in Carbon-Wall (CFC) conditions with similar divertor geometry.