Scientific and technical activities on JET focus on the issues likely to affect the ITER design and operation. The physics of the ITER reference mode of operation, the ELMy H-mode, has progressed significantly: the extrapolation of ELM size to ITER has been re-evaluated; NTMs have been shown to be meta-stable in JET, and can be avoided via sawtooth destabilisation by ICRH; a-simulation experiments were carried out by accelerating 4He beam ions by ICRH, providing a new tool for fast particle and MHD studies with up to 80-90% of plasma heating by fast 4He ions. With or without impurity seeding, quasi-steady sate high confinement (H98=1), high density (ne/nGR = 0.9-1) and high b (bN =2) ELMy H-mode has been achieved by operating near the ITER triangularity (d~0.40-0.5) and safety factor (q95~3), at Zeff~1.5-2. In Advanced Tokamak scenarios, internal transport barriers are now characterised in real time with a new criterion r*T; tailoring of the current profile with LHCD provides reliable access to a variety of q profiles, with significantly lowered access power for barrier formation; rational q surfaces appear to be associated with ITB formation; Alfven cascades are observed in RS plasmas, providing an identification of q profile evolution; plasmas with "current holes" were observed and explained by modelling. Transient high confinement Advanced Tokamak regimes with H89 = 3.3, bN = 2.4 and ITER relevant q<5 are achievable in reversed magnetic shear. Quasi-stationary internal transport barriers are developed with full non-inductive current drive, including ~50% bootstrap current. Record duration of ITBs was achieved, up to 11 s, approaching the resistive time. Pressure and current profiles of Advanced Tokamak regimes are controlled by a real time feedback system, in separate experiments. The erosion and co-deposition data base progressed significantly, in particular with a new quartz-microbalance diagnostic allowing shot by shot measurements of co-deposition.