The impact of carbon and beryllium/tungsten as plasma-facing components on plasma radiation, divertor power and particle fluxes, and plasma and neutral conditions in the divertors has been assessed in JET both experimentally and by simulations for plasmas in low confinement mode. In high-recycling conditions the studies show a 30% reduction in total radiation in the scrape-off layer when replacing carbon with beryllium in the main chamber and tungsten in the divertor. Correspondingly, at the low field side divertor plate a two-fold increase in power conducted to the plate and a two-fold increase in electron temperature at the strike point were measured. In low-recycling conditions the SOL was found to be nearly identical for both materials configurations. These observations are in qualitative agreement with predictions from the fluid edge code package EDGE2D/EIRENE. The rollover of the ion currents to both plates was measured to occur at 30% higher upstream densities and radiated power fraction in the Be/W configuration. Past rollover, it was possible to reduce the ion currents to the low field side targets by a factor of 2 and to operate in stable, detached conditions in the JET-ILW configuration; in the JET-C configuration the reduction was limited to 50%. Plasmas with low and high triangularity (and thus magnetic separation to the top of the device), and horizontal and vertical target configurations were investigated and compared to EDGE2D/EIRENE predictions.